KMID : 0829320090120040193
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Korean Journal of Clinical Microbiology 2009 Volume.12 No. 4 p.193 ~ p.200
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Comparison of the MicroScan¨Þ Combo Panel Synergies plus with the MicroScan¨Þ Conventional Combo Panel for Diagnostic Performance of Gram-negative and Gram-positive Bacteria
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Uh Young
Jang In-Ho Lee Kwan-Soo Kwon Oh-Gun Yoon Kap-Jun
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Abstract
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Background: To access the clinical usefulness of MicroScan¨Þ Synergies plus Combo Panels (Siemens, USA) for the identification and antimicrobial susceptibility test (AST) of Gram-negative bacteria (GNB) and Gram-positive cocci (GPC), we compared MicroScan¨Þ Synergies plus Combo Panels with MicroScan¨Þ conventional Combo Panels.
Methods: One-hundred four isolates of GNB were simultaneously tested with MicroScan¨Þ Synergies plus Neg Combo Type 2 Panel (SINC2) and MicroScan¨Þ Neg Combo Panel Type 44 (NC44). One-hundred isolates of GPC were simultaneously tested with MicroScan¨Þ Synergies plus Pos Combo 3 Panel (SIPC3) and MicroScan¨Þ Pos Combo 1A (PC1A).
Results: Of the GNB isolates, agreement rate of identification between SINC2 and NC44 were 92.3% to the species level and 93.3% to the genus level. Of the GPC isolates, agreement rate of identification between SIPC3 and PC1A were 85.0% to the species level and 100% to the genus level. Of the GNB isolates, agreement rate of AST according to antimicrobial agents between SINC2 and NC44 ranged from 86.5% to 100%. Among GPC isolates, agreement rate of AST according to antimicrobial agents between SIPC3 and PC1A were higher than 96.0% with the exception of gentamicin and quinupristin-dalfopristin.
Conclusion: Compared with MicroScan¨Þ conventional Combo Panels (NC44, PC1A), MicroScan¨Þ Synergies plus Combo Panels (SINC2, SIPC3) showed high agreement rate of identification and AST, and had the advantage of more rapid reporting.
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KEYWORD
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MicroScan¨Þ, Identification, Antimicrobial susceptibility test
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